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A Tissue Phantom Model for Training Residents in Ultrasound-guided Liver Biopsy

Rationale and Objectives

The apprenticeship model for training of percutaneous liver biopsy has limitations, and costs of commercially available simulation models can be prohibitive. We created an inexpensive tissue phantom for liver biopsy simulation and evaluated the utility of this model for training radiology residents.

Materials and Methods

A bovine–porcine tissue phantom was devised as a simulation model and consisted of bovine liver with a porcine rib layer and inserted pimento olives simulating target lesions. Training sessions (a 20-minute didactic lecture and a 90-minute practice session) were offered to all residents in a diagnostic radiology residency. Effect of training was assessed by questionnaire before and after training. Level of knowledge of topics covered in the didactic session, confidence in technical skills, and anxiety level were evaluated on a five-point scale (1, poor to 5, excellent).

Results

Thirty-five of 38 residents received training on the models (∼$40). Mean reported value score for training was 4.88/5. Improvement was greatest for knowledge of technique (2.3–4.1/5, P < .001) and knowledge of postprocedure care (2.2–4.1/5, P < .001). Technical confidence increased (2.4–3.8/5, P < .001) and anxiety related to performing liver biopsy improved (2.7–3.7/5, P < .001). Residents with no prior experience in liver biopsy ( n = 21) had significantly greater increases in all categories than residents with prior experience ( n = 14), except for knowledge about obtaining informed consent and anxiety levels.

Conclusions

Utilization of an inexpensively created bovine/porcine liver biopsy simulation model was well perceived by radiology residents and can be used as an educational tool during residency.

Ultrasound guidance for procedures is a skill used in many radiology subspecialty areas, such as body imaging, interventional radiology, mammography, and musculoskeletal radiology. Proficiency with ultrasound-guided (US-guided) procedures should be a part of a radiology residency core curriculum.

Percutaneous liver biopsy is a commonly performed procedure for staging of diffuse liver disease and diagnosis of hepatic lesions; however, it does carry the risk of hemorrhage, biliary leak, injury to adjacent structures, and even death . Ultrasound guidance for nontargeted liver biopsy can significantly decrease complication rate from 2.1% for blinded liver biopsy to 0.53% for those with ultrasound guidance . Learning to perform liver biopsies under ultrasound guidance also provides a solid foundation for percutaneous interventions on other solid organs and is a necessary step before performing targeted liver biopsies.

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Methods

Study Design

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Creation of a Bovine–Porcine Tissue Phantom

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Figure 1, Bovine–porcine tissue phantom. Porcine rib layer simulating the chest wall and allowing for practice targeting the liver between ribs ( white arrow ), whole or halved cow liver ( open arrow ), sutures to keep the porcine rib/chest wall layer in place ( curved arrow ).

Figure 2, Ultrasound images of the model. Excellent visualization of the porcine chest wall (*), hepatic parenchyma ( white arrow ) and pimento olive target lesions ( black arrow ) was obtained.

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Selection of Participants

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Training Sessions

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Table 1

Didactic Topics

Didactic lecture content (20 minutes) Indications for nontargeted and targeted biopsy Target selection Coagulation parameters Informed consent and specific risks of liver biopsy Considerations for pain control and/or conscious sedation Collaboration with nursing and pathology colleagues Technique: equipment setup, preliminary imaging and selection of an entry site, preprocedure time out, sterile technique, local anesthesia, breathing instructions, needle deployment, and sample handling Postprocedure care

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Results

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Figure 3, Ultrasound images of a target lesion before (a) and after biopsy (b) showing the needle positioned superficial to the lesion (→) and with the needle tip through the lesion (→).

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Survey Results

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Table 2

Survey Results

Survey Query Mean Preintervention Rating (Scale 1–5) Mean Postintervention Rating (Scale 1–5) Wilcoxon Signed Rank Test, P Value Indications 2.7 4.2 <.001 Informed consent 3.4 4.4 <.001 Target selection 2.3 4.0 <.001 Coagulation parameters 2.7 4.4 <.001 Local anesthesia 2.7 4.4 <.001 Technique 2.3 4.1 <.001 Postprocedure instructions 2.2 4.1 <.001 Technical confidence 2.4 3.8 <.001 Anxiety 2.7 3.7 <.001

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Discussion

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Conclusions

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Appendix

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Appendix 1

Preintervention Survey

Item Number Query Response 1 In what year of training are you? PGY 2 PGY 3 PGY 4 PGY 5 2 How many ultrasound guided core biopsies of any abdominal organ have you performed? None 1–5 >5–10 >10–20 >20 3 How many liver biopsies have you performed? None 1–5 >5–10 >10–20 >20 4 How knowledgeable do you consider yourself regarding the following components of the procedure? (Rank from 1–5, 1 = no knowledge, 5 = extremely knowledgeable) Indications for liver biopsy 1 2 3 4 5 Informed consent 1 2 3 4 5 Feasibility of lesions/approach 1 2 3 4 5 Coagulation parameters 1 2 3 4 5 Local anesthesia and pain control 1 2 3 4 5 Technique 1 2 3 4 5 Postprocedure instructions 1 2 3 4 5 5 How confident are you in your technical skills? (Rank from 1–5: 1 = lack confidence, 5 = extremely confident) 1 2 3 4 5 6 How do you estimate your anxiety level prior to performing this procedure on a patient? (Rank from 1–5: 1 = extremely anxious, 5 = not anxious) 1 2 3 4 5

PGY, postgraduate year.

Appendix 2

Postintervention Survey

Item Number Query Response 1 How many liver biopsies did you perform on the phantom during the simulation? None 1–2 3–4 5–6 ≥7 2 How knowledgeable do you consider yourself regarding the following components of the procedure? (Rank from 1–5, 1 = no knowledge, 5 = extremely knowledgeable) Indications for liver biopsy 1 2 3 4 5 Informed consent 1 2 3 4 5 Feasibility of lesions/approach 1 2 3 4 5 Coagulation parameters 1 2 3 4 5 Local anesthesia and pain control 1 2 3 4 5 Technique 1 2 3 4 5 Postprocedure instructions 1 2 3 4 5 3 How confident are you in your technical skills? (Rank from 1–5: 1 = lack confidence, 5 = extremely confident) 1 2 3 4 5 4 How do you estimate your anxiety level prior to performing this procedure on a patient? (Rank from 1–5: 1 = extremely anxious, 5 = not anxious) 1 2 3 4 5 5 How helpful did you find the simulation training? (Rank from 1–2: 1 = not helpful, 5 = extremely helpful) 1 2 3 4 5 6 Any comments/suggestions?

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