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Dose Reduction in Pediatric Computed Tomography with Automated Exposure Control

Rationale and Objectives

Since the introduction of computed tomographic (CT) imaging in the 1970s, the number of examinations has increased steadily. CT imaging is an essential part of routine workup in diagnostic radiology. The great advantage of multidetector computed tomography is the acquisition of a large amount of data in a short time period, thus speeding up diagnostic procedures. To protect patients from unnecessary radiation exposure, different approaches have been developed. In this study, the efficacy of automated exposure control (AEC) software in multidetector CT imaging with a focus on dose reduction in pediatric examinations was assessed.

Materials and Methods

Between August 2004 and September 2005, a total of 71 children (40 male, 31 female; age range, 2–13 years; mean age, 7.2 years) were examined using a multisource CT scanner. Three different regions (chest, upper abdomen, and pelvis) were examined. Overall image quality was assessed with a subjective scale (1 = excellent, 2 = diagnostic, 3 = nondiagnostic). For all examinations, AEC was used. From the scanner’s patient protocol, dose-length product, volume CT dose index, and tube current–time product were calculated for each examination.

Results

With AEC, a mean dose reduction of 30.6% was calculated. Images were rated as excellent ( n = 39) or diagnostic ( n = 32). Nondiagnostic image quality was not seen. Dose-length product and volume CT dose index were reduced by 30.4% and 29.5%, respectively. Overall, a mean dose reduction of 30.1% of the effective dose (5.8 ± 3.1 vs 8.4 ± 4.6 mSv) was achieved ( P < .001).

Conclusions

With AEC software, a mean dose reduction of 30% without any loss in diagnostic image quality is possible.

The number of computed tomographic (CT) examinations, especially in children, is rising steadily. It is known that children are more sensitive to ionizing radiation and face a higher risk for developing malignancy because of their longer life expectancy compared to adults . In general, radiation-free imaging modalities must be considered when imaging children, or whenever indicated if radiation exposure can be lowered or even minimized . Vendors of CT scanners have addressed this issue by developing different dose reduction software to reduce tube current in a sinusoidal way while correlating individual anatomy in real time . Recently, a new dose reduction software (CARE Dose 4D; Siemens Healthcare, Forchheim, Germany) was introduced, in which tube current values are adapted to individual patient anatomy prior to the CT exam. This type of automatic exposure control combines the attenuation-based online tube current modulation presented in earlier studies with an automated evaluation of patient anatomy and setting of exposure parameters for every slice. The purpose of this study was to evaluate this new software in pediatric CT scans, with a special focus on the level of dose reduction and effects on image quality.

Materials and methods

A total of 71 consecutive pediatric patients (41 male, 30 female; age range 2–13 years; mean age, 7.2 years) were included from August 2004 to September 2005. CT scans were performed on a multidetector CT system (Somatom Sensation 64; Siemens Healthcare). Care Dose 4D software uses data from the prescan projection radiogram (topogram) to determine “ideal” tube current values for each z-position by calculating object attenuation. The projection data acquired for the topogram measure the patient’s attenuation for every z-position and allow calculation of the optimal tube current for the projection angle used, anteroposterior or lateral. Evaluation of the attenuation profile’s shape is applied to estimate the attenuation perpendicular to the projection angle and calculate the optimal tube current for this angle. The adequate tube current–time product for this z-position is derived as the average of the two tube current values multiplied by the rotation time. During the scan, the online tube current modulation calculates and applies the optimal tube current for each projection angle. From these data, the software controls the CT scan and adapts tube current values for each z-position. Performed CT scans included three different regions (chest, upper abdomen, and pelvis). From the individual patient protocol information dose-length product, volume CT dose index, and tube current–time product were calculated for each examination. This prospective study was approved by the local ethics committee, and written informed consent was obtained.

Scan Parameters

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Quantitative Assessment

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Table 1

Body Weight–Adapted Tube Current–Time Product Values

Body Weight (kg) Chest (mAs) Abdomen/Pelvis (mAs) 0–8.9 40 60 9–17.9 50 70 18–26.9 60 80 27–35.9 70 100 36–44.9 80 120 45–69.9 100 140 >70 100 160

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Qualitative Assessment

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Results

Quantitative Assessment

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Table 2

Comparison of Mean Dose Values with and without AEC and Rate of Mean Dose Reduction for DLP, CTDIvol, and Effective Dose Values

Without AEC With AEC Reduction rate (%)P ∗ DLP (mGy/cm) 457.4 ± 280.8 318.7 ± 184.3 30.4 <.001 CTDIvol 10.9 ± 3.2 7.7 ± 2.1 29.5 <.001 Effective dose (mSv) 8.4 ± 4.6 5.8 ± 3.1 30.1 <.001

AEC, automated exposure control; CTDIvol, volume computed tomography dose index; DLP, dose-length product.

Data are expressed as mean ± standard deviation.

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Figure 1, Mean dose reduction values for specific scan regions with calculated reduction rates.

Table 3

Calculated Mean Dose Reduction Values per Exam Region

Region_n_ Mean Dose Reduction (%) Thorax 41 31.6 Upper abdomen 24 27.6 Pelvis 6 28.0

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Qualitative Assessment

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Table 4

Qualitative Assessment of Image Quality

Category_n_ % 1 (excellent) 39 54 2 (diagnostic) 32 46 3 (nondiagnostic) 0 0

Figure 2, Example of a computed tomographic scan of excellent image quality.

Figure 3, Example of a computed tomographic scan of diagnostic image quality.

Figure 4, Example of a computed tomographic scan showing neuroblastoma cranial to the level of kidneys, with all anatomic structures delineated accurately and image quality rated as very good.

Figure 5, Example of a coronal reformat from a volume computed tomographic scan with the dose reduction technique.

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Discussion

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Conclusions

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References

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