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Spectral Beam Shaping in Unenhanced Chest CT Examinations

Rationale and Objectives

This study aimed to determine the optimal tube potential for unenhanced chest computed tomographies (CTs) with age-related phantoms.

Materials and Methods

Three physical anthropomorphic phantoms (newborn, 5-year-old child, and adult) were scanned on a third-generation dual-source CT using CAREkV in semi-mode and CAREDose4D (ref. KV: 120; ref. mAs 50). Scans were performed with all available tube potentials (70–150 kV and Sn150 kV). The lowest volume computed tomography dose index (CTDI vol ) was selected to perform additional Sn100-kV scans with matched and half (Sn100-half) CTDI vol value. Image quality was evaluated on the basis of contrast-to-noise ratio (CNR).

Results

For the newborn phantom, 70–110 kV was selected as the optimal range (0.36–0.37 mGy). Using Sn150 kV led to an increase in radiation dose (0.75 mGy) without improving CNR (96.9 vs 101.5). Sn100-half showed a decrease in CNR (73.1 vs 101.5). The lowest CTDI vol for the child phantom was achieved between 100 and 120 kV (0.78–0.80 mGy). Using Sn150 kV increased radiation dose (1.02 mGy) without improvement of CNR (92.4 vs 95.8). At Sn100-half CNR was decreased (61.4 vs 95.8). For adults, 140 and 150 kV revealed the lowest CTDI vol (2.68 and 2.67 mGy). The Sn150 kV scan delivered comparable CNR (54.4 vs 56.6), but a lower CTDI vol (2.08 mGy). At Sn100-half CNR was comparable to the 150 kV scan (58.1 vs 56.6).

Conclusion

Unenhanced chest CT performed at 100 kV or 150 kV with tin filtration enables radiation dose reduction for the adult phantom, but not for the pediatric phantoms.

Introduction

For the evaluation of pulmonary pathologies, computed tomography (CT) is the method of choice due to its high spatial and inherent contrast resolution. Especially for patients with dyspnea or for pediatric patients, high-pitch protocols can provide high-quality images despite the presence of patient motion . Based on the ALARA (“as low as reasonably achievable”) principle, notably pediatric patients should receive the lowest achievable radiation dose owing to the increased radiosensitivity of children. To minimize the potential risks associated with radiation exposure, different techniques have been established to reduce the radiation dose , including automatic tube current modulation, lower tube voltage settings , and iterative image reconstruction techniques .

The third generation dual-source computed tomography (DSCT) system is able to adjust the tube voltage in narrow 10-kV steps ranging from 70 kV to150 kV and is additionally equipped with increased generator power. The scanner also includes Stellar Infinity detectors, which incorporate the advantages of integrated circuit design in the original Stellar detector while increasing spatial resolution because of a 25% increase in the number of detector channels and the addition of a two-dimensional antiscatter grid. Due to the resulting noise reduction in low-dose CTs, low-voltage examinations can be applied in a wider range, especially in contrast-enhanced angiographic studies . Furthermore, it is endued with a novel protocol using a tin-filtered 100 kVp (Sn100 kVp) and 150 kVp spectrum (Sn150 kVp) in single-energy dual-source acquisition mode. This thin absorber tin filter with a thickness of 0.6 mm absorbs primarily low-energy photons that contribute little to noncontrast image quality but increase the radiation dose burden for the patient.

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Materials and Methods

Phantoms

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Figure 1, Transaxial CT images of anthropomorphic thoracic phantoms. Both anteroposterior and lateral patient dimensions are indicated. CT, computed tomography.

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CT Acquisition Protocol

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Phantom Analysis

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Radiation Dose

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Results

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Figure 2, Graphs show changes in CNR, which are plotted as a function of tube potential for newborn, 5-year–old, and adult phantoms. For each phantom tube current had been adapted by using CAREDose4D and CAREkV in semi-mode. CNR, contrast-to-noise ratio.

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TABLE 1

CTDI vol and Tube Current (mAs) for all Phantom Sizes and all Kilovoltage Settings

Phantom Size kV CTDI vol (mGy) Effective mAs Newborn 70 0.37 31 80 0.36 18 90 0.36 12 100 0.37 9 110 0.37 7 120 0.45 6 130 0.58 7 140 0.69 7 150 0.81 7 Sn150 0.75 25 5-Year-old 70 0.91 77 80 0.85 44 90 0.82 28 100 0.80 20 110 0.78 15 120 0.78 11 130 0.85 10 140 0.89 9 150 0.95 8 Sn150 1.02 35 Adult 70 5.74 491 80 4.40 229 90 3.59 124 100 3.19 79 110 2.94 56 120 2.81 42 130 2.76 33 140 2.68 27 150 2.67 23 Sn150 2.08 71

CTDI vol , volume computed tomography dose index.

CAREDose4D and CAREkV in semi-mode were used for all the scans.

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TABLE 2

Comparison of CTDI vol , CNR, and σ M Between the Different Tube Potentials, Which Provide the Lowest Dose for the Newborn Phantom and the Two Different Tube Voltages Using Spectral Shaping (Sn100 and Sn150)

Tube Potential (kV) CTDI vol (mGy) CNR σ M 70 0.37 100.7 8.0 80 0.36 94.5 8.6 90 0.36 101.5 7.9 100 0.37 90.8 9.0 110 0.37 104.1 8.0 Sn150 0.75 96.9 8.4 Sn100-full \* 0.36 112.5 6.8 Sn100-half \* 0.18 73.1 11.3

CNR, contrast-to-noise ratio; CTDI vol , volume computed tomography dose index.

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TABLE 3

Comparison of CTDI vol , CNR, and σ M Between the Different Tube Potentials, Which Provide the Lowest Dose for the 5-Year-Old Phantom and the Two Different Tube Voltages Using Spectral Shaping (Sn100 and Sn150)

Tube Potential (kV) CTDI vol (mGy) CNR σ M 100 0.80 83.5 10.2 110 0.78 95.8 8.2 120 0.78 85.4 9.6 Sn150 1.02 92.4 9.4 Sn100-full \* 0.78 92.1 9.6 Sn100-half \* 0.39 61.4 13.9

CNR, contrast-to-noise ratio; CTDI vol , volume computed tomography dose index.

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TABLE 4

Comparison of CTDI vol , CNR, and σ M Between the Different Tube Potentials, Which Provide the Lowest Dose for the Adult Phantom and the Two Different Tube Voltages Using Spectral Shaping (Sn100 and Sn150)

Tube Potential (kV) CTDI vol (mGy) CNR σ M 140 2.68 59.3 14.6 150 2.67 56.6 15.0 Sn150 2.08 54.4 16.3 Sn100-full \* 2.67 73.3 11.4 Sn100-half \* 1.33 58.1 14.6

CNR, contrast-to-noise ratio; CTDI vol , volume computed tomography dose index.

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Discussion

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Acknowledgments

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