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How to Critically Appraise the Clinical Literature

Recent efforts have been made to standardize the critical appraisal of clinical health care research. In this article, critical appraisal of diagnostic test accuracy studies, screening studies, the...

Higher Glutamate + Glutamine and Reduction of N -acetylaspartate in Posterior Cingulate According to Age Range in Patients with Cognitive Impairment and/or Pain

Rationale and Objectives The aim of the study was to analyze 1) whether the metabolite levels in the posterior cingulate cortex (PCC) are different in healthy individuals compared to a group of pa...

Effect of Prevalence Expectations on Radiologists' Behavior

We read with great interest the article, “Can prevalence expectations drive radiologists’ behavior?” by Reed et al. in the April 2014 issue of the Academic Radiology . We would like to laud Reed et...

Differentiation of Lipoma From Liposarcoma on MRI Using Texture and Shape Analysis

Rationale and Objectives To determine if differentiation of lipoma from liposarcoma on magnetic resonance imaging can be improved using computer-assisted diagnosis (CAD). Materials and Methods F...

Decision Support

Imaging utilization and the appropriateness of the imaging in the specific clinical scenario is a main focus of health policy discussions today. On April 1, 2014, President Obama signed a patch to ...

Breast DCE-MRI

Rationale and Objectives Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) scanning protocols vary widely. The purpose of this study was to determine the effects of postcontras...

Assessing Treatment Response of Osteolytic Lesions by Manual Volumetry, Automatic Segmentation, and RECIST in Experimental Bone Metastases

Rationale and Objectives Aim of the study was to compare between volumetric and unidimensional approaches for treatment response monitoring in a nude rat model of experimental bone metastases. For...

Assessing the Impact of Prevalence Expectations on Radiologists' Behavior

We would like to thank Dr Vikas Chaudhary and Dr Shahina Bano for their interest and encouraging comments regarding our recently published article . We also appreciate the opportunity to discuss an...

Appropriateness and Imaging Utilization

Modern imaging methods have been transformative in improving medical care. Cross-sectional imaging has largely eliminated the need for invasive “exploratory” surgery and is widely used to triage ac...

Applying Quantitative Benefit–Risk Analysis to Aid Regulatory Decision Making in Diagnostic Imaging

Rationale and Objectives Health agencies making regulatory marketing-authorization decisions use qualitative and quantitative approaches to assess expected benefits and expected risks associated w...