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MR Spectroscopy Using Normalized and Non-normalized Metabolite Ratios for Differentiating Recurrent Brain Tumor from Radiation Injury

Rationale and Objectives To compare the ability of normalized versus non-normalized metabolite ratios to differentiate recurrent brain tumor from radiation injury using magnetic resonance spectros...

Measuring Anisotropic Diffusion in Kidney Using MRI

Rationale and Objectives To measure the anisotropic diffusion in kidney and to demonstrate the feasibility of renal tractography. Materials and Methods Diffusion tensor imaging was acquired in k...

Making Sense of the Evidence

The US system of health care has been subject to numerous criticisms, citing costly and inefficient care delivery, fragmented and heterogeneous resource utilization, and lower life expectancy per h...

Innovation in Diagnostic Imaging Services

Innovation in the field of diagnostic imaging is based primarily on the availability of new and improved equipment that opens the door for new clinical applications. Payments for these imaging proc...

Influence of Population Prevalences on Numbers of False Positives

Background Disease prevalence alters the number of true positives (TP), true negatives (TN), false negatives (FN), and false positives (FP), even if the sensitivity and specificity of a test stays...

Enabling Comparative Effectiveness Research with Informatics

Rationale Both outcomes researchers and informaticians are concerned with information and data. As such, some of the central challenges to conducting successful comparative effectiveness research ...

Computer Disease Simulation Models

Computer disease simulation models are increasingly being used to evaluate and inform health care decisions across medical disciplines. The aim of researchers who develop these models is to integra...

Comparison of CT Perfusion and Digital Subtraction Angiography in the Evaluation of Delayed Cerebral Ischemia

Rationale and Objectives Delayed cerebral ischemia (DCI) is a devastating condition that occurs secondary to aneurysmal subarachnoid hemorrhage (A-SAH). The purpose is to compare computed tomograp...

Comparative Effectiveness Research in Radiology

Health care costs continue to rise, with significant geographic differences in spending on health care and outcomes within the United States. The goal of comparative effectiveness research is to re...

Characterization and Detection of Physiologic Lung Changes Before and After Placement of Bronchial Valves Using Hyperpolarized Helium-3 MR Imaging

Rationale and Objectives The aim of this study was to determine the efficacy of hyperpolarized 3 He (HHe) ventilation and apparent diffusion coefficient (ADC) HHe magnetic resonance imaging (MRI)...