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During one of my college summers I helped the publisher of a weekly newspaper in the next county publish a centennial issue. It involved a month of interviewing people and writing biographical sket...

Seventy-five and counting

A few days before this is written and a few months before you read it, I passed my 75th birthday. It was a fairly quiet day. I worked on a book, took a nap in the afternoon, and had dinner with som...

Reliable and Computationally Efficient Maximum-Likelihood Estimation of “Proper” Binormal ROC Curves

Rationale and Objectives Estimation of ROC curves and their associated indices from experimental data can be problematic, especially in multireader, multicase (MRMC) observer studies. Wilcoxon est...

Linear Versus Web-Style Layout of Computer Tutorials for Medical Student Learning of Radiograph Interpretation

Rationale and Objective We sought to determine which is more effective in increasing skill in radiograph interpretation: a linear (PowerPoint-style) computer tutorial that locks the student into a...

In Vitro Effect of Focused Ultrasound or Thermal Stress on HSP70 Expression and Cell Viability in Three Tumor Cell Lines

Rationale and Objectives In this study, we compared the effect of focused ultrasound with the effect of thermal stress on the induction of a heat inducible promoter in an in vitro model using thre...

High Resolution Multidetector CT-Aided Tissue Analysis and Quantification of Lung Fibrosis

Rationale and Objectives Volumetric high-resolution scans can be acquired of the lungs with multidetector CT (MDCT). Such scans have potential to facilitate useful visualization, characterization,...

Gray and White Matter Delineation in the Human Spinal Cord Using Diffusion Tensor Imaging and Fuzzy Logic

Rationale and Objectives Diffusion tensor imaging (DTI) has been used extensively in determining morphology and connectivity of the brain; however, similar analysis in the spinal cord has proven d...

Gain in Signal-to-Noise for First-Pass Contrast-Enhanced Abdominal MR Angiography at 3 Tesla Over Standard 1.5 Tesla Prediction with a Computer Model

Rationale and Objectives To estimate the gain in signal-to-noise ratio (SNR) in first-pass contrast-enhanced (CE) abdominal magnetic resonance angiography (MRA) at 3.0 T compared with 1.5 T. Mate...

Dynamic-Threshold Level Set Method for Volumetry of Porcine Kidney in CT Images

Rationale and Objective We sought to assess the accuracy of a novel computerized volumetry method, called dynamic-thresholding (DT) level set, in determining the renal volume of pigs in CT images ...

Diffusion-Weighted and Diffusion Tensor Imaging in Fibromyalgia Patients A Prospective Study of Whole Brain Diffusivity, Apparent Diffusion Coefficient, and Fraction Anisotropy in Different Regions of the Brain and Correlation With Symptom Severity

Fibromyalgia (FM) is a chronic pain condition characterized by widespread pain and tenderness that afflicts 2%–4% of the population in industrialized countries ( ). It is the second most common rhe...