Rationale and Objectives To compare the performance of two shortened breast magnetic resonance imaging (MRI) protocols to a standard MRI protocol for breast cancer screening. Materials and Method...

Rationale and Objectives The aim of the work described here was to determine the feasibility of monitoring Na + concentration and distribution in muscle/skin during aerobic/anaerobic exercise wit...

Overdiagnosis refers to the detection of cancers that would never come to light in a patient’s lifetime and are only identified by means of screening. Exactly how much overdiagnosis currently exist...

Alzheimer disease (AD), a progressive neurodegenerative disease that causes dementia, affects millions of elderly Americans and represents a growing problem with the aging of the population. There ...

Rationale and Objectives Hyperpolarized 3 He magnetic resonance imaging (MRI) ventilation abnormalities are visible in ex-smokers without airflow limitation, but the clinical relevance of this is...

Osteoporosis is a highly prevalent disease that predisposes patients to fragility fractures. These fractures carry serious risks, including increased mortality and the potential loss of functional ...

In the optimism surrounding screening for lung cancer, the downsides of screening should not be ignored. The article examines the dark side of screening, which is not an unmitigated good. Cautious...

Pulmonary embolism (PE) is a dreaded condition which nearly every physician, in practice or training, is aware about. It is a leading and avoidable cause of sudden death . That PE is now overdiagno...

There is a trade-off between overdiagnosis or overtreatment and underdiagnosis or undertreatment because of partial information. Furthermore, the information problem creates an equivalence for the ...

Rationale and Objectives After a half century of clinical trials, expansive observations, vigorous advocacy and debate, screening mammography could not be in a more controversial condition, especi...