“The delivery of good medical care is to do as much nothing as possible” . That sentence is the 13th law of Samuel Shem’s The House of God , a satirical novel portraying intern life. Despite ...

Rationale and Objectives In this review we will discuss the historic development of intracranial aneurysms as a pathologic entity and the potential for overdiagnosis. Materials and Methods We co...

Asymptomatic microscopic hematuria (AMH) is relatively common in clinical practice but the etiology remains unclear in the majority of patients; it is rarely related to genitourinary malignancies. ...

Radiologist Saurabh “Harry” Jha still recalls the first time he was on call for radiology in the United States. He received simultaneous emergency requests for a head computed tomography (CT) and c...

Precision Medicine promises to get the right patient, the right test, the right diagnosis, the right treatment, and in the right amount. Is this hope or hype? Precision medicine (PM) is much talke...

At first glance, it is counterintuitive that imaging, the alleged instigator of overdiagnosis, can reduce overdiagnosis and overtreatment. Imaging can curb overdiagnosis if it juxtaposes between th...

Rationale and Objectives The purpose of this study was to compare the precision of mammographic breast density measurement using radiologist reader assessment, histogram threshold segmentation, fu...

The first steps in reducing overdiagnosis are to acknowledge that overdiagnosis exists and to appreciate that overdiagnosis is a problem worth reducing. If one accepts the former but disagrees with...

Mild traumatic brain injury (m-TBI) is a public health problem, particularly in veterans and athletes. Often synonymous with “concussion,” m-TBI is head injury accompanied by acute-phase characteri...

Rationale and Objectives To analyze the statistical biases in the studies used to derive cardiac magnetic resonance–based major and minor criteria for the diagnosis of arrhythmogenic right ventric...